Rupatadine Impurity 2 CAS 1422960-88-0 (free base)
| CAS No. | 1422960-88-0 (free base) |
| Molecular Formula | C33H34ClN4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rupatadine Impurity 2 (CAS 1422960-88-0 (free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C33H34ClN4Cl and a molecular weight of 557.56 g/mol.
The molecular framework of Rupatadine Impurity 2 (C33H34ClN4Cl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rupatadine Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H34ClN4 Cl |
| Molecular Weight | 557.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Rupatadine Standards
- Rupatadine Impurity 21 (CAS 1007089-84-0)
- Rupatadine Impurity 24 (CAS 100910-66-5)
- Rupatadine Impurity 3 (CAS 102074-19-1)
- Rupatadine impurity 1 (CAS 1118754-56-5)
- Rupatadine impurity 14 (CAS 1210824-61-5)
- Rupatadine EP Impurity C (CAS 1224515-72-3)
- Rupatadine Impurity 4 (CAS 1235342-53-6)
- Rupatadine EP Impurity A (CAS 1354055-68-7)
Recommended Standards
- Salbutamol Impurity 60 (CAS 238762-31-7)
- Josamycin Impurity 8 (CAS CATO-C4X-30158)
- Riociguat EP Impurity A (CAS 625115-52-8)
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- Octahydro-1H-4,7-methanoisoindole Hydrochloride (CAS 1269456-02-1)
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- 2-((2-Chlorobenzyl)thio)-N-methyl-5,6,7,8-tetrahydroquinazolin-4-amine (CAS 339019-32-8)
- 4-Methoxy-N'-(thieno[2,3-b]quinoline-2-carbonyl)benzenesulfonohydrazide (CAS 692260-16-5)
- 4-Bromo-2,2-dimethyl-3-fluoropropiophenone (CAS 898766-27-3)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com